Bioengineered Protein Fibers with Anti‐Freezing Mechanical Behaviors

Abstract Most biological protein fibers exhibit extraordinary mechanical performance at room temperatures but inferior freezing resistance. Maintaining fiber's high strength and toughness under subzero conditions remains a great challenge. Herein, class of tolerant is reported with favorable ice‐phobic capacity cryogenic by genetic engineering. Inspired nature, chimeric recombinant proteins consist highly ordered structural domains antifreeze (AFP) modules, showing excellent ice recrystallization inhibition activity. Such features endow the resulting remarkable properties good stability in environments. In stark contrast to conventional fibers, engineered maintain stiffness even −20 −40 °C. The synergistic contribution AFP plays an important role for anti‐freezing behaviors. Thus, this study pioneers engineering approach next generation tailored applications extreme settings.